When Paul Hogan saw how his mother's care for her mother (his grandmother) yielded better health and a better, longer life for his grandmother, it provided him with inspiration to start his own business providing such care for others. He formed Home Instead Senior Care. The story of how he did this and turned the company into an organization with franchises all over the world was in the New York Times on Sunday, February 14, 2010.
Here is a link. It is a story worth reading because it shows how personal experience of seeing a real need for real people can be translated into a solid business that fills that need. This is the essence of what it takes to be a successful entrepreneur.